Transferrin Receptor Protein (AA 89-760) (His tag)
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- Target See all Transferrin Receptor (TFRC) Proteins
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 89-760
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Transferrin Receptor protein is labelled with His tag.
- Sequence
- AA 89-760
- Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Biological Activity Comment
- Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized rh CD71 /TFR at 10 μg/mL ( 100 μL/well ) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/mL.
- Top Product
- Discover our top product TFRC Protein
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Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (Fc Tag)
TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transferrin Receptor (p90, CD71) (TFRC) protein (His-Avi Tag)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-Avi Tag,Biotin)TFRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His tag)TFRC Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His tag)TFRC Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (GST tag)TFRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) protein (His-DYKDDDDK-Strep II Tag)TFRC Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) (Active) protein (His tag)TFRC Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) (Active) protein (His tag,Biotin)TFRC Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Alternative Name
- CD71 (TFRC Products)
- Background
- CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
- Molecular Weight
- 77.0 kDa
- NCBI Accession
- NP_003225
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
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