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EFNA4 Protein (Ephrin A4) (AA 26-171) (Fc Tag)

EFNA4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181030
$878.46
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  • Target See all EFNA4 Proteins
    EFNA4 (Ephrin A4 (EFNA4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 26-171
    Origin
    • 10
    • 4
    • 3
    Human
    Source
    • 6
    • 5
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This EFNA4 protein is labelled with Fc Tag.
    Sequence
    AA 26-171
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 43 kDa. The protein migrates as 48 kDa and 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    EFNA4 (Ephrin A4 (EFNA4))
    Alternative Name
    Ephrin-A4 (EFNA4 Products)
    Synonyms
    EFNA4, EFL-4, Epl4, LERK-4, EFL4, EPLG4, LERK4, ephrin A4, ephrin-A4 L homeolog, ephrin-A4, EFNA4, efna4.L, efna4, Efna4
    Background
    Ephrin-A4 (EFNA4) is also known as EPH-related receptor tyrosine kinase ligand 4 (LERK4), EPLG4, which belongs to the ephrin family. EFNA4 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA4 is cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA4 may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
    Molecular Weight
    43.0 kDa
    Pathways
    RTK Signaling
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