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EFNA4 Protein (His tag,Fc Tag)

EFNA4 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318438
  • Target See all EFNA4 Proteins
    EFNA4 (Ephrin A4 (EFNA4))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 10
    • 4
    • 3
    Human
    Source
    • 5
    • 5
    • 4
    • 2
    Human Cells
    Purification tag / Conjugate
    This EFNA4 protein is labelled with His tag,Fc Tag.
    Purpose
    Recombinant Human Ephrin-A4/EFNA4 Protein (Fc & His Tag)(Active)
    Sequence
    Leu26-Gly171
    Characteristics
    Recombinant Human Ephrin-A4 is produced by our Mammalian expression system and the target gene encoding Leu26-Gly171 is expressed with a Fc, 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human EphA7-His(Cat: PKSH033689) at 2μg/ml(100 μl/well) can bind Human EFNA4-Fc-6His. The ED50 of Human EFNA4-Fc-6His is 1.5190 ug/ml .
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    Discover our top product EFNA4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    EFNA4 (Ephrin A4 (EFNA4))
    Alternative Name
    Ephrin-A4/EFNA4 (EFNA4 Products)
    Synonyms
    EFNA4 Protein, EFL-4 Protein, Epl4 Protein, LERK-4 Protein, EFL4 Protein, EPLG4 Protein, LERK4 Protein, ephrin A4 Protein, ephrin-A4 L homeolog Protein, ephrin-A4 Protein, EFNA4 Protein, efna4.L Protein, efna4 Protein, Efna4 Protein
    Background

    Background: Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. Ephrin-A4 consists of approximately 125 amino acids and includes four invariant cysteines, It has been shown to bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. Ephrin-A4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. It may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

    Synonym: Ephrin-A4, EPH-Related Receptor Tyrosine Kinase Ligand 4, LERK-4, EFNA4, EPLG4, LERK4

    Molecular Weight
    44.3 kDa
    UniProt
    P52798
    Pathways
    RTK Signaling
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