CLEC4G Protein (AA 55-293) (Fc Tag)
(1 reference)Quick Overview for CLEC4G Protein (AA 55-293) (Fc Tag) (ABIN2444087)
Target
See all CLEC4G ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 55-293
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Purification tag / Conjugate
- This CLEC4G protein is labelled with Fc Tag.
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Sequence
- AA 55-293
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Characteristics
- This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.1 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 1-294) protein (His tag)
custom-made CLEC4G Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 1-293) protein (His tag)custom-made CLEC4G Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -71 °C. Avoid repeated freeze-thaw cycles.
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: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
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: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
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- CLEC4G (C-Type Lectin Domain Family 4, Member G (CLEC4G))
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Alternative Name
- LSECtin
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Background
- C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.
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Molecular Weight
- 52.1 kDa
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NCBI Accession
- NP_940894
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UniProt
- Q6UXB4
Target
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