FGF acidic (Active) Protein

Catalog No. ABIN2468429

This Recombinant FGF acidic protein is produced in Escherichia coli (E. coli).

Quick Overview for FGF acidic (Active) Protein (ABIN2468429)

Target: FGF acidic

Protein Type: Recombinant

Biological Activity: Active

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: < 95 % by SDS-PAGE gel and HPLC analyses.

Product Details

Sequence: MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Characteristics: Biological activity was determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 is < 0.1 ng/mL, in the presence of 10 μg/mL heparin, corresponding to a specific activity of > 1 x 10⁷ units/mg.

Endotoxin Level: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Handling Advice: As with any protein, exposing FGF-acidic recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -20 °C

Storage Comment: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted FGF-acidic stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Expiry Date: 24 months

Target Details

Target: FGF acidic

Alternative Name: FGF-Acidic

Background: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

Gene ID: 25317

NCBI Accession: NP_036978

OMIM: 6978839

UniProt: P61149