Resistin Protein (RETN)
Quick Overview for Resistin Protein (RETN) (ABIN2469020)
Target
See all Resistin (RETN) ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MPSMSLCPMD EAISKKINQD FSSLLPAAMK NTVLHCWSVS SRGRLASCPE GTTVTSCSCG SGCGSWDVRE DTMCHCQCGS IDWTAARCCT LRVGS
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Resistin (RETN) (Active) protein
RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Resistin (RETN) (AA 17-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 21-114) protein (Fc Tag)RETN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 16-108) protein (His-IF2DI Tag)RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Resistin (RETN) (AA 1-108) protein (GST tag)RETN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Resistin (RETN) (AA 19-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Resistin (RETN) protein (Myc-DYKDDDDK Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- Resistin (RETN)
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Alternative Name
- Resistin
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Background
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin s ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant rat Resistin is a 20.0 kDa disulfide-linked homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond.
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Gene ID
- 246250
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NCBI Accession
- NP_653342
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OMIM
- 21426805
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UniProt
- Q8K4J7
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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