Resistin Protein (RETN)
Quick Overview for Resistin Protein (RETN) (ABIN2469024)
Target
See all Resistin (RETN) ProteinsProtein Type
Origin
Source
Purity
-
-
Sequence
- SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
-
Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Resistin (RETN) (Active) protein
RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Resistin (RETN) (AA 17-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 21-114) protein (Fc Tag)RETN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 16-108) protein (His tag)RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Resistin (RETN) (AA 1-108) protein (GST tag)RETN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Resistin (RETN) (AA 19-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Resistin (RETN) protein (Myc-DYKDDDDK Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Handling Advice
- As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
-
Storage
- -20 °C
-
Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
-
Expiry Date
- 24 months
-
-
- Resistin (RETN)
-
Alternative Name
- Resistin
-
Background
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
-
Gene ID
- 57264
-
NCBI Accession
- NP_001191888
-
OMIM
- 326368221
-
UniProt
- Q99P87
-
Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
-
