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CD200 Protein (CD200) (Fc Tag)

This Recombinant CD200 protein is produced in HEK-293 Cells.
Catalog No. ABIN2566377

Quick Overview for CD200 Protein (CD200) (Fc Tag) (ABIN2566377)

Target

See all CD200 Proteins
CD200

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 10
  • 2
  • 1
Human

Source

  • 14
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Western Blotting (WB), ELISA

Purity

>95 % as determined by SDS-PAGE.
  • Purification tag / Conjugate

    This CD200 protein is labelled with Fc Tag.

    Characteristics

    Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD200R1 at 2 μg/mL,the concentration of rhCD200 Fc Chimera that produces 50 % of the optimal binding response is appoximately 2. 0-16 ng/mL.

    Fusion tag: C-Fc Tag

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  • Application Notes

    This recombinant protein can be used for WB, ELISA. For research use only.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    50 mM tris, 100 mM glycine, pH 7.5

    Storage

    -80 °C,-20 °C

    Storage Comment

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target

    CD200

    Alternative Name

    CD200

    Background

    CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

    Molecular Weight

    48.6 kDa

    Gene ID

    4345

    UniProt

    P41217
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