CD4 Protein (CD4) (His tag)

Catalog No. ABIN2566413

This Recombinant CD4 protein is produced in HEK-293 Cells.

Quick Overview for CD4 Protein (CD4) (His tag) (ABIN2566413)

Target: CD4

Protein Type: Recombinant

Origin: Cynomolgus

Source: HEK-293 Cells

Application: Western Blotting (WB)

Purity: >95 % as determined by SDS-PAGE.

Product Details

Purification tag / Conjugate: This CD4 protein is labelled with His tag.

Application Details

Application Notes: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -80 °C,-20 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Target Details

Target: CD4

Alternative Name: CD4

Background: T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Molecular Weight: 42.3 kDa

UniProt: G7N5T8

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events