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Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag)

This Recombinant Coronin 7 protein is produced in HEK-293 Cells.
Catalog No. ABIN2712510

Quick Overview for Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag) (ABIN2712510)

Target

See all Coronin 7 (CORO7) Proteins
Coronin 7 (CORO7)

Protein Type

Recombinant

Origin

  • 2
  • 2
  • 1
Human

Source

  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Coronin 7 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human Coronin-7 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Coronin 7 (CORO7)

    Background

    This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants some of which form read-through transcripts with a neighboring gene.

    Molecular Weight

    100.4 kDa

    NCBI Accession

    NP_078811
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