Claudin 19 Protein (CLDN19) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Claudin 19 Protein (CLDN19) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2712853)
Target
See all Claudin 19 (CLDN19) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Claudin 19 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Claudin-19 / CLDN19 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Claudin 19 (CLDN19) (AA 1-224) protein (His tag)
custom-made CLDN19 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 19 (CLDN19) (AA 1-224) protein (His tag)custom-made CLDN19 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Claudin 19 (CLDN19) (AA 1-211) protein (GST tag)CLDN19 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Claudin 19 (CLDN19) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CLDN19 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Claudin 19 (CLDN19)
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Alternative Name
- Claudin-19,cldn19
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Background
- The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
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Molecular Weight
- 23 kDa
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NCBI Accession
- NP_683763
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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