CARD9 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for CARD9 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713168)
Target
See all CARD9 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This CARD9 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CARD9 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
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Alternative Name
- Card9
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Background
- The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
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Molecular Weight
- 62.1 kDa
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NCBI Accession
- NP_434700
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Pathways
- Activation of Innate immune Response
Target
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