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MICU1 Protein (His tag)

Recombinant MICU1 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2713250

Quick Overview for MICU1 Protein (His tag) (ABIN2713250)

Target

See all MICU1 Proteins
MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Protein Type

Recombinant

Origin

  • 4
  • 2
Human

Source

  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This MICU1 protein is labelled with His tag.

    Characteristics

    • Recombinant human CBARA1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
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    Conjugate His tag
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

    Alternative Name

    Cbara1

    Background

    This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

    Molecular Weight

    54.4 kDa

    NCBI Accession

    NP_006068
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