CHAC1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for CHAC1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713952)
Target
See all CHAC1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This CHAC1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CHAC1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
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Alternative Name
- Chac1
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Background
- This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.
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Molecular Weight
- 23.6 kDa
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NCBI Accession
- NP_001136248
Target
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