ABI1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ABI1 Proteins
- ABI1 (Abl-Interactor 1 (ABI1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ABI1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ABI1 / SSH3BP1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ABI1 Protein
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Abl-Interactor 1 (ABI1) (AA 185-238) protein (GST tag)
ABI1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Abl-Interactor 1 (ABI1) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)ABI1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Abl-Interactor 1 (ABI1) (Transcript Variant 12) protein (Myc-DYKDDDDK Tag)ABI1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ABI1 (Abl-Interactor 1 (ABI1))
- Alternative Name
- Abi1,ssh3bp1 (ABI1 Products)
- Background
- This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(1011) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
- Molecular Weight
- 54.9 kDa
- NCBI Accession
- NP_005461
- Pathways
- RTK Signaling, Response to Water Deprivation, ER-Nucleus Signaling
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