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Adrenomedullin Protein (ADM) (Myc-DYKDDDDK Tag)

Recombinant Adrenomedullin protein expressed in HEK-293 Cells.
Catalog No. ABIN2714435

Quick Overview for Adrenomedullin Protein (ADM) (Myc-DYKDDDDK Tag) (ABIN2714435)

Target

See all Adrenomedullin (ADM) Proteins
Adrenomedullin (ADM)

Protein Type

Recombinant

Origin

  • 5
  • 3
  • 2
  • 2
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  • 2
Human

Source

  • 16
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Adrenomedullin protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human Adrenomedullin / ADM protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Adrenomedullin (ADM)

    Target Type

    Hormone

    Background

    The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration.

    Molecular Weight

    20.2 kDa

    NCBI Accession

    NP_001115

    Pathways

    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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