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ALOX5AP Protein (Myc-DYKDDDDK Tag)

This Recombinant ALOX5AP protein is produced in HEK-293 Cells.
Catalog No. ABIN2714586

Quick Overview for ALOX5AP Protein (Myc-DYKDDDDK Tag) (ABIN2714586)

Target

See all ALOX5AP Proteins
ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Protein Type

Recombinant

Origin

  • 3
  • 2
Human

Source

  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This ALOX5AP protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human ALOX5AP / FLAP protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

    Alternative Name

    Alox5ap,flap

    Background

    This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

    Molecular Weight

    18 kDa

    NCBI Accession

    NP_001620
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