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AP2M1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

AP2M1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714769
$1,112.40
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20 μg
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  • Target See all AP2M1 Proteins
    AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This AP2M1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human AP2 complex subunit mu-1 / AP2M1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
    Alternative Name
    Ap2 Complex Subunit mu-1,ap2m1 (AP2M1 Products)
    Synonyms
    AP50 Protein, CLAPM1 Protein, mu2 Protein, Ap50 Protein, Clapm1 Protein, cb34 Protein, Ap2m1 Protein, dpy-23 Protein, sb:cb34 Protein, zgc:55711 Protein, zgc:85653 Protein, wu:fa97a10 Protein, ap2m1-a Protein, ap2m1 Protein, zgc:56643 Protein, AP2M1 Protein, adaptor related protein complex 2 mu 1 subunit Protein, adaptor-related protein complex 2, mu 1 subunit Protein, adaptor-related protein complex 2, mu 1 subunit, a Protein, adaptor related protein complex 2 mu 1 subunit L homeolog Protein, adaptor-related protein complex 2, mu 1 subunit, b Protein, AP-2 complex subunit mu-1 Protein, clathrin coat assembly protein AP50 Protein, clathrin coat assembly protein ap50 Protein, AP2M1 Protein, Ap2m1 Protein, ap2m1a Protein, ap2m1.L Protein, ap2m1b Protein, ap2m1 Protein, cgd8_950 Protein, PY06523 Protein, PVX_118455 Protein, PVX_123590 Protein, CpipJ_CPIJ003697 Protein
    Background
    This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    49.2 kDa
    NCBI Accession
    NP_001020376
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
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