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APOA1 Protein (Myc-DYKDDDDK Tag)

This Recombinant APOA1 protein is produced in HEK-293 Cells.
Catalog No. ABIN2714817

Quick Overview for APOA1 Protein (Myc-DYKDDDDK Tag) (ABIN2714817)

Target

See all APOA1 Proteins
APOA1 (Apolipoprotein A-I (APOA1))

Protein Type

Recombinant

Origin

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Human

Source

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HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This APOA1 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human Apolipoprotein A I / APO AI protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    APOA1 (Apolipoprotein A-I (APOA1))

    Alternative Name

    Apolipoprotein A I (Apo Ai)

    Background

    This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.

    Molecular Weight

    28.9 kDa

    NCBI Accession

    NP_000030

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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