CHTOP Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715454

This Recombinant CHTOP protein is expressed in HEK-293 Cells.

Quick Overview for CHTOP Protein (Myc-DYKDDDDK Tag) (ABIN2715454)

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CHTOP protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human C1orf77 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Alternative Name: c1orf77

Background: This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 26.2 kDa

NCBI Accession: NP_056422