Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719393

This Recombinant Deoxyguanosine Kinase protein is expressed in HEK-293 Cells.

Quick Overview for Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2719393)

Target: Deoxyguanosine Kinase (DGUOK)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Deoxyguanosine Kinase protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Deoxyguanosine kinase (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Deoxyguanosine Kinase (DGUOK)

Alternative Name: Deoxyguanosine Kinase

Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Molecular Weight: 27.9 kDa

NCBI Accession: NP_550438

Pathways: Ribonucleoside Biosynthetic Process