EIF4G1 Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)
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- Target See all EIF4G1 Proteins
- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 5
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EIF4G1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EIF4G1 / EIF4F (transcript variant 5) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EIF4G1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3764-75, (2015) (PubMed).
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DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3764-75, (2015) (PubMed).
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- Target
- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
- Alternative Name
- Eif4g1,eif4f (EIF4G1 Products)
- Synonyms
- EIF4GI Protein, CG10811 Protein, Dmel\\CG10811 Protein, EIF4G Protein, Eif4G Protein, deIF4G Protein, eIF-4G Protein, eIF4g Protein, p200 Protein, EIF4G1 Protein, wu:fb50a05 Protein, wu:fc60b06 Protein, eif4g Protein, CUCUMOVIRUS MULTIPLICATION 2 Protein, CUM2 Protein, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G Protein, eukaryotic translation initiation factor 4G Protein, DDBDRAFT_0217646 Protein, DDBDRAFT_0217647 Protein, DDBDRAFT_0234257 Protein, DDB_0217646 Protein, DDB_0217647 Protein, DDB_0234257 Protein, NV18824 Protein, EIF-4G1 Protein, EIF4F Protein, P220 Protein, PARK18 Protein, p220 Protein, E030015G23Rik Protein, eIF4GI Protein, eukaryotic translation initiation factor 4 gamma 1 Protein, eukaryotic translation initiation factor 4G Protein, eukaryotic translation initiation factor 4 gamma, 1a Protein, eukaryotic translation initiation factor 4 gamma, 1 S homeolog Protein, eukaryotic initiation factor Protein, eukaryotic translation initiation factor 4 gamma Protein, eukaryotic translation initiation factor 4 gamma, 1 Protein, eukaryotic translation initiation factor 4, gamma 1 Protein, EIF4G1 Protein, eIF4G Protein, eif4g1a Protein, LOC704923 Protein, eif4g1.S Protein, EIF4G Protein, eIF4g Protein, Eif4g Protein, Eif4g1 Protein
- Background
- The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
- Molecular Weight
- 154.6 kDa
- NCBI Accession
- NP_004944
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