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EIF6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Recombinant EIF6 protein expressed in HEK-293 Cells.
Catalog No. ABIN2720114

Quick Overview for EIF6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2720114)

Target

See all EIF6 Proteins
EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Protein Type

Recombinant

Origin

  • 5
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Human

Source

  • 12
  • 4
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Purification tag / Conjugate

    This EIF6 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human EIF6 / ITGB4BP (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

    Alternative Name

    Eif6,itgb4bp

    Background

    Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

    Molecular Weight

    26.4 kDa

    NCBI Accession

    NP_852133

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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