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FBLIM1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant FBLIM1 protein is produced in HEK-293 Cells.
Catalog No. ABIN2720916

Quick Overview for FBLIM1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2720916)

Target

See all FBLIM1 Proteins
FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Protein Type

Recombinant

Origin

  • 6
  • 2
  • 2
  • 1
Human

Source

  • 5
  • 3
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This FBLIM1 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human FBLIM1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

    Alternative Name

    Fblim1

    Background

    This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Molecular Weight

    40.5 kDa

    NCBI Accession

    NP_060026
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