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Frataxin Protein (FXN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FXN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721410
  • Target See all Frataxin (FXN) Proteins
    Frataxin (FXN)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 9
    • 4
    • 2
    • 1
    Human
    Source
    • 10
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Frataxin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Frataxin (FXN) (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FXN Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Frataxin (FXN)
    Abstract
    FXN Products
    Background
    This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to > 90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    18.8 kDa
    NCBI Accession
    NP_000135
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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