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Frataxin Products

(Frataxin (FXN))

Categories

This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].

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Featured Frataxin Categories

Frataxin Antibodies

High quality antibodies with extensive validation data.

Frataxin ELISA Kits

Reliable ELISA kits for a wide range of species.

Frataxin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Frataxin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (8)
Cat. No. ABIN7259416
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, StM, WB
Validations
  • (5)
Cat. No. ABIN6939442
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN3022481
Quantity 100 μL
Datasheet Datasheet

Recommended Frataxin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955989
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4993459
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1133692
Quantity 96 tests
Datasheet Datasheet

Recommended Frataxin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080234
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080235
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354551
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Frataxin products

Sanchez, Chapdelaine, Rousseau, Raymond, Corbeil, Tremblay: "Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique." in: Mitochondrion, Vol. 30, pp. 59-66, (2016) (PubMed).

Tsai, Barondeau: "Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." in: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).

Thierbach, Drewes, Fusser, Voigt, Kuhlow, Blume, Schulz, Reiche, Glatt, Epe, Steinberg, Ristow: "The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals." in: The Biochemical journal, Vol. 432, Issue 1, pp. 165-72, (2010) (PubMed).

Mariño, Zaldivar, Mesa, Mederos, Rodríguez, Gotay, Labrada, Ochoa, Macleod, Pérez: "Low predisposition to instability of the Friedreich ataxia gene in Cuban population." in: Clinical genetics, Vol. 77, Issue 6, pp. 598-600, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Synonyms and alternative names related to Frataxin

frataxin (fxn), frataxin (LOC100284365), frataxin (TVAG_182150), frataxin (fh), frataxin (FTX1), frataxin (FXN), frataxin (Fxn), BcDNA:AT09528, CG8971, CyaY, DFH, Dfh, dfh, Dmel\\CG8971, FA, FARR, FRDA, Frda, LOC100284365, RGD1565754, X25, zgc:158218

Protein level used designations for Frataxin

  • DKEYP-118A9.1
  • frataxin, mitochondrial
  • frataxin
  • CG8971-PA
  • CG8971-PB
  • fh-PA
  • fh-PB
  • frataxin homologue
  • frataxin-like
  • Friedreich ataxia protein
  • Friedreich ataxia
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