Frataxin Protein (FXN) (AA 42-210) (His tag)
-
- Target See all Frataxin (FXN) Proteins
- Frataxin (FXN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 42-210
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Frataxin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Frataxin, 42-210aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product FXN Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
- Storage
- 4 °C
-
- Target
- Frataxin (FXN)
- Alternative Name
- Frataxin (FXN Products)
- Synonyms
- zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
- Background
- Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein. NCBI no.: NP_000135
- Molecular Weight
- 21.1 kDa (190aa), confirmed by MALDI-TOF.
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
-