Fukutin Protein (FKTN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Fukutin Protein (FKTN) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721450)
Target
See all Fukutin (FKTN) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Fukutin protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Fukutin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Fukutin (FKTN) (AA 1-461) protein (His tag)
custom-made FKTN Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fukutin (FKTN) (AA 1-461) protein (His tag)custom-made FKTN Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Fukutin (FKTN)
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Alternative Name
- Fukutin
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Background
- The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.
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Molecular Weight
- 53.5 kDa
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NCBI Accession
- NP_001073270
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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