LMAN1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724845

Recombinant LMAN1 protein expressed in HEK-293 Cells.

Quick Overview for LMAN1 Protein (Myc-DYKDDDDK Tag) (ABIN2724845)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This LMAN1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human LMAN1 / ERGIC53 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Alternative Name: Lman1,ergic53

Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.

Molecular Weight: 54.2 kDa

NCBI Accession: NP_005561