MAPT Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725487

Product Details

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MAPT protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MAPT / TAU (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: Mapt,tau (MAPT Products)

Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer&aposs disease, Pick&aposs disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Molecular Weight: 45.7 kDa

NCBI Accession: NP_005901

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size