MFN2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all MFN2 Proteins
- MFN2 (Mitofusin 2 (MFN2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MFN2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Mitofusin-2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MFN2 Protein
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Mitofusin 2 (MFN2) (AA 1-757) protein (His tag)
custom-made MFN2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mitofusin 2 (MFN2) (AA 1-757) protein (His tag)custom-made MFN2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mitofusin 2 (MFN2) (AA 661-757) protein (GST tag)MFN2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitofusin 2 (MFN2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MFN2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 168-82, (2015) (PubMed).
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: "MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 168-82, (2015) (PubMed).
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- Target
- MFN2 (Mitofusin 2 (MFN2))
- Alternative Name
- Mitofusin-2 (MFN2 Products)
- Background
- This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
- Molecular Weight
- 86.2 kDa
- NCBI Accession
- NP_001121132
- Pathways
- Skeletal Muscle Fiber Development
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