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Myotilin Protein (MYOT) (His tag)

Recombinant Myotilin protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2726723
$396.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
Shipping to: United States
Will be delivered in 11 Business Days

Quick Overview for Myotilin Protein (MYOT) (His tag) (ABIN2726723)

Target

See all Myotilin (MYOT) Proteins
Myotilin (MYOT)

Protein Type

Recombinant

Origin

  • 6
  • 3
Human

Source

  • 3
  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Myotilin protein is labelled with His tag.

    Characteristics

    • Recombinant human Myotilin (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Myotilin (MYOT)

    Alternative Name

    Myotilin

    Background

    This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008]

    Molecular Weight

    55.2 kDa

    NCBI Accession

    NP_006781
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