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Myotilin Protein (MYOT) (His tag)

Recombinant Myotilin protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2726723

Quick Overview for Myotilin Protein (MYOT) (His tag) (ABIN2726723)

Target

See all Myotilin (MYOT) Proteins
Myotilin (MYOT)

Protein Type

Recombinant

Origin

  • 4
  • 3
Human

Source

  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Myotilin protein is labelled with His tag.

    Characteristics

    • Recombinant human Myotilin (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Myotilin (MYOT)

    Alternative Name

    Myotilin

    Background

    This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008]

    Molecular Weight

    55.2 kDa

    NCBI Accession

    NP_006781
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