NBL1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for NBL1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2726864)
Target
See all NBL1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This NBL1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human NBL1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) protein (His tag)
NBL1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 17-181) protein (His-IF2DI Tag)NBL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuroblastoma 1, DAN Family BMP Antagonist (NBL1) (AA 1-180) protein (GST tag)NBL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))
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Alternative Name
- Nbl1
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Background
- This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed.
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Molecular Weight
- 17.6 kDa
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NCBI Accession
- NP_005371
Target
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