Quick Overview for NR1H2 Protein (Myc-DYKDDDDK Tag) (ABIN2727542)
Target
See all NR1H2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This NR1H2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human NR1H2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-446) protein (His tag)
custom-made NR1H2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-460) protein (His tag)custom-made NR1H2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2) (AA 1-461) protein (GST tag)NR1H2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))
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Alternative Name
- Nr1h2
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Background
- The liver X receptors, LXRA (NR1H3 MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].
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Molecular Weight
- 50.9 kDa
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NCBI Accession
- NP_009052
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding
Target
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