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NUMB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Recombinant NUMB protein expressed in HEK-293 Cells.
Catalog No. ABIN2727803

Quick Overview for NUMB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2727803)

Target

See all NUMB Proteins
NUMB (Numb Homolog (NUMB))

Protein Type

Recombinant

Origin

  • 7
  • 4
  • 1
Human

Source

  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This NUMB protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human NUMB (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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    Conjugate Strep Tag
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    NUMB (Numb Homolog (NUMB))

    Alternative Name

    Numb

    Background

    Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]

    Molecular Weight

    70.6 kDa

    NCBI Accession

    NP_001005743

    Pathways

    Cell-Cell Junction Organization
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