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PCBP4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Recombinant PCBP4 protein expressed in HEK-293 Cells.
Catalog No. ABIN2728358

Quick Overview for PCBP4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2728358)

Target

See all PCBP4 Proteins
PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

Protein Type

Recombinant

Origin

  • 3
  • 2
  • 1
Human

Source

  • 3
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 3

    Purification tag / Conjugate

    This PCBP4 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human PCBP4 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

    Alternative Name

    Pcbp4

    Background

    This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

    Molecular Weight

    41.3 kDa

    NCBI Accession

    NP_127501
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