Peroxiredoxin 3 Protein (PRDX3) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728705

This Recombinant Peroxiredoxin 3 protein is expressed in HEK-293 Cells.

Quick Overview for Peroxiredoxin 3 Protein (PRDX3) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728705)

Target: Peroxiredoxin 3 (PRDX3)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Peroxiredoxin 3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Peroxiredoxin-3 / PRDX3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: Peroxiredoxin-3,prdx3

Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

Molecular Weight: 21.4 kDa

NCBI Accession: NP_006784

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process