PZP Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729566

This Recombinant PZP protein is expressed in HEK-293 Cells.

Quick Overview for PZP Protein (Myc-DYKDDDDK Tag) (ABIN2729566)

Target: PZP (Pregnancy Zone Protein (PZP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This PZP protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Pregnancy-zone protein (PZP) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PZP (Pregnancy Zone Protein (PZP))

Alternative Name: Pregnancy-Zone Protein (Pzp)

Background: The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer&aposs disease patients.

Molecular Weight: 163.7 kDa

NCBI Accession: NP_002855