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RNF34 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Recombinant RNF34 protein expressed in HEK-293 Cells.
Catalog No. ABIN2730782

Quick Overview for RNF34 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2730782)

Target

See all RNF34 Proteins
RNF34 (Ring Finger Protein 34 (RNF34))

Protein Type

Recombinant

Origin

  • 6
  • 3
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 3
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Purification tag / Conjugate

    This RNF34 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human RFI / RNF34 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36
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    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    RNF34 (Ring Finger Protein 34 (RNF34))

    Alternative Name

    Rfi,rnf34

    Background

    The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

    Molecular Weight

    41.5 kDa

    NCBI Accession

    NP_079402
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