SAG Protein (Myc-DYKDDDDK Tag)
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- Target See all SAG Proteins
- SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SAG protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human S-arrestin / SAG protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SAG Protein
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S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 1-405) protein (His tag)
custom-made SAG Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 1-403) protein (His tag)custom-made SAG Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) (AA 1-405), (full length) protein (His tag)SAG Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))
- Alternative Name
- S-Arrestin,sag (SAG Products)
- Background
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
- Molecular Weight
- 44.9 kDa
- NCBI Accession
- NP_000532
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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