Quick Overview for SIP1 Protein (Myc-DYKDDDDK Tag) (ABIN2732069)
Target
See all SIP1 (GEMIN2) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SIP1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SIP1 / GEMIN2 (transcript variant alpha) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) protein (His tag)
custom-made GEMIN2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-269) protein (His tag)custom-made GEMIN2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) protein (GST tag)GEMIN2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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Alternative Name
- Sip1,gemin2
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Background
- This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
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Molecular Weight
- 31.4 kDa
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NCBI Accession
- NP_003607
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
Target
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