SMARCE1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for SMARCE1 Protein (Myc-DYKDDDDK Tag) (ABIN2732241)
Target
See all SMARCE1 ProteinsProtein Type
Origin
Source
Application
Purity
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                                            Purification tag / Conjugate
- This SMARCE1 protein is labelled with Myc-DYKDDDDK Tag.
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                                            Characteristics
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                        - Recombinant human SMARCE1 / BAF57 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
 
 
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                                            Application Notes
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                        Recombinant human proteins can be used for:
 Native antigens for optimized antibody production
 Positive controls in ELISA and other antibody assays
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                                            Comment
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                        The tag is located at the C-terminal. 
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                                            Restrictions
- For Research Use only
 
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                                            Concentration
- 50 μg/mL
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                                            Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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                                            Storage
- -80 °C
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                                            Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
 
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    - SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
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                                            Alternative Name
- Smarce1,baf57
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                                            Background
- The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
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                                            Molecular Weight
- 46.5 kDa
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                                            NCBI Accession
- NP_003070
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                                            Pathways
- Chromatin Binding
 Target
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