SPAG6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for SPAG6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2732491)
Target
See all SPAG6 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This SPAG6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SPAG6 / PF16 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Sperm Associated Antigen 6 (SPAG6) (AA 1-507) protein (His tag)
custom-made SPAG6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sperm Associated Antigen 6 (SPAG6) (AA 1-509) protein (His tag)custom-made SPAG6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sperm Associated Antigen 6 (SPAG6) (AA 1-458) protein (GST tag)SPAG6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SPAG6 (Sperm Associated Antigen 6 (SPAG6))
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Alternative Name
- Spag6,pf16
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Background
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 49.5 kDa
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NCBI Accession
- NP_758442
Target
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