TCL1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for TCL1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2733366)
Target
See all TCL1A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This TCL1A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TCL1A / TCL1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-114) protein (His tag)
custom-made TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-116) protein (His tag)custom-made TCL1A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-114) proteinTCL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
T-Cell Leukemia/lymphoma 1A (TCL1A) (AA 1-114) protein (GST tag)TCL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
T-Cell Leukemia/lymphoma 1A (TCL1A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TCL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Alternative Name
- Tcl1a,tcl1
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Background
- Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010].
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Molecular Weight
- 13.3 kDa
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NCBI Accession
- NP_068801
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Pathways
- Stem Cell Maintenance
Target
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