UBA7 Protein (Myc-DYKDDDDK Tag)
Quick Overview for UBA7 Protein (Myc-DYKDDDDK Tag) (ABIN2734767)
Target
See all UBA7 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This UBA7 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human UBA7 / UBE1L protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
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Alternative Name
- Uba7,ube1l
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Background
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
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Molecular Weight
- 111.5 kDa
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NCBI Accession
- NP_003326
Target
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