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UBA7 Protein (Myc-DYKDDDDK Tag)

This Recombinant UBA7 protein is produced in HEK-293 Cells.
Catalog No. ABIN2734767

Quick Overview for UBA7 Protein (Myc-DYKDDDDK Tag) (ABIN2734767)

Target

See all UBA7 Proteins
UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

Protein Type

Recombinant

Origin

Human

Source

  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This UBA7 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human UBA7 / UBE1L protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

    Alternative Name

    Uba7,ube1l

    Background

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

    Molecular Weight

    111.5 kDa

    NCBI Accession

    NP_003326
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