VKORC1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all VKORC1 Proteins
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VKORC1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human VKORC1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VKORC1 Protein
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Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 1-163) protein (His tag)
custom-made VKORC1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) (AA 1-163) protein (GST tag)VKORC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Alternative Name
- Vkorc1 (VKORC1 Products)
- Background
- This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 9.7 kDa
- NCBI Accession
- NP_996560
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