WRAP53 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for WRAP53 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735538)
Target
See all WRAP53 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This WRAP53 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human WDR79 / TCAB1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) protein (His tag)
custom-made WRAP53 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) protein (GST tag)WRAP53 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)WRAP53 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)WRAP53 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)WRAP53 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
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Alternative Name
- Wdr79,tcab1
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Background
- This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene.
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Molecular Weight
- 59.1 kDa
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NCBI Accession
- NP_001137462
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Pathways
- Telomere Maintenance
Target
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