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X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) protein (His tag) Protein

XRCC3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2735693
$326.70
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50 μg
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  • Target
    XRCC3
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This XRCC3 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human XRCC3 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    XRCC3
    Synonyms
    CMM6, 4432412E01Rik, AI182522, AW537713, MGC69118, im:7142103, zgc:101608, si:dkey-11b8.1, xrcc3, XRCC3, X-ray repair cross complementing 3, X-ray repair complementing defective repair in Chinese hamster cells 3, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog, XRCC3, Xrcc3, xrcc3.L, xrcc3
    Background
    This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
    Molecular Weight
    37.9 kDa
    NCBI Accession
    NP_005423
    Pathways
    DNA Damage Repair
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