ZAP70 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ZAP70 Proteins
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ZAP70 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ZAP70 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ZAP70 Protein
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zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-619) protein (His tag)
custom-made ZAP70 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-493) protein (GST tag)ZAP70 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP, KAA
zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 397-493) protein (GST tag)ZAP70 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) proteinZAP70 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
- Alternative Name
- Zap70 (ZAP70 Products)
- Background
- This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
- Molecular Weight
- 69.7 kDa
- NCBI Accession
- NP_001070
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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