METRNL Protein (DYKDDDDK Tag)

Catalog No. ABIN2745741

Product Details

Target: METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This METRNL protein is labelled with DYKDDDDK Tag.

Application: SDS-PAGE (SDS)

Purpose: Meteorin-like (mouse) (rec.)

Cross-Reactivity: Mouse

Characteristics: Mouse meteorin-like [IL-41] (46-311) is fused at the N-terminus to a FLAG®-tag.

Purity: >95 % (SDS-PAGE)

Endotoxin Level: <0.1EU/μg purified protein (LAL test).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile water.

Concentration: 0.1 mg/mL

Buffer: Contains PBS.

Handling Advice: After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))

Alternative Name: Meteorin-like (METRNL Products)

Background:

Interleukin-41, IL-41, IL41, Metrnl, Subfatin, Cometin

Meteorin-like (interleukin-41, cometin, subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.

Molecular Weight: ~35kDa (SDS-PAGE), ~ 40 kDA (Monomer) (SEC)

UniProt: Q8VE43